SAM-e Go to Top

S-Adenosylmethionine (SAM-e) is a naturally occurring sulphur-containing physiologic compound found in every living cell of the human body. It is one of the most active methyl donor produced in the human body and is involved in more than one hundred biochemical pathways and specific processes. It has been studied extensively for its therapeutic use and proven to have regulating effect on mood and brain functions, supports joint health and keeps the liver healthy.

Gnosis S.p.A. is the inventor and largest manufacturer of SAM-e in the World with patented all natural SAM-e. The company offers both finished formulation (tablets) and bulk from USA and Switzerland respectively.

The product is completely vegetarian and solvent free; manufactured by yeast fermentation process. The active content in the salt (S,S) isomer is more than 65% unlike 50% or lower offered by other manufacturers.

The product is offered as bulk powder, tablets of 200mg and 400mg as standalone and combination formualtions: SAMe + Silybin, SAMe + Quatrefolic and SAMe + Chondroitin. more


Vitamk7® (Vitamin K2-7) Go to Top

Vitamin K2 -7, called menaquinone-7 (MK7), demonstrated its unique effect and potential benefits on bone metabolism and heart disease. MK-7 is the most active form of vitamin K2 with highest bioavailability.

VitamK7 ® from Gnosis S.p.A consists entirely of natural, all trans Menaquinone-7. It is solvent-free and obtained from Bacillus subtilis natto cultures through a patented biofermentation process.

The product is available in powder form and oil form, suitable for different dosages and formulations. VitamK7® powder is offered in 1000ppm; 2000ppm, 2500ppm. VitamK7® Oil in 1500ppm and higher concentrations. It also offers K2&OliveTM – combination of MK-7 and Olive oil.

Gnosis is the only company with human clinical studies for health indication of MK-7. more


Extrafolate® ((6R,S)-5-MTHF Calcium Salt)Go to Top

Extrafolate® is the calcium salt of (6R,S)-5-methyltetrahydrofolic acid (Racemic mixure) which is the biologically active form of the B-vitamin folic acid.

It can be used as a valid alternative to folates supplementation for reducing homocysteine levels and supporting normal cellular proliferation, vascular endothelial function, cardiovascular health and nervous system function.

Folates are extensively studied for prenatal care, cardio health, depression & dementia, diabetic neuropathy.

Gnosis S.p.A. offers this product in pure S form (active) as well under the brand name of Extrafolate-S®. more


Quatrefolic® ((6S)-5-MTHF Glucosamine salt)Go to Top

Quatrefolic® is the glucosamine salt of (6S)-5-Methyltetrahydrofolate. It is the fourth generation folate (biologically active form of the B-vitamin folic acid) endowed with a long lasting stability and peculiarly high water solubility as well as an improved bioavailability and established safety.

The unique room temperature stability profile makes it easier to handle in all facets of commercialization, development, manufacturing, and consumer products.

Gnosis S.p.A has a worldwide patent for Quatrefolic® and the name and logo are protected by copyright. Gnosis has well established safety data for use of Quatrefolic® even during pregnancy. It has GRAS status, the EFSA approval and NDI approval from the US FDA. This product was granted the NBT Award as the “Most Effective Strategic Product Development” in 2011.

Folates are extensively studied for prenatal care, cardio health, depression & dementia, diabetic neuropathy. more


Phosphocomplex™ (Silybin Phosphatidylcholine Complex)Go to Top

Silybin is the most active of the flavanolignans contained in milk thistle and has been studied for its benefits in Liver Health.

Phosphatidylcholine complexation offered by Gnosis S.p.A is a relatively new and a far superior product for Liver health with potent antioxidant effect. Phosphocomplex™ is obtained from the complexation of Silybin with phosphatidylcholine.

Phosphatidylcholine complexation of Silybin helps enhance the capacity of Silybin to cross the lipid-rich bio-membranes and reach circulation, resulting in enhanced bioavailability. It has better pharmacokinetic profile with 8-10 folds higher bioavailability than Silymarin (parent source) along with optimal tolerability profile with established safety and efficacy.


GSH (Glutathione)Go to Top

This endogenous tripeptide (glycin, cysteine & glutamic acid) is present in almost all cells of the body playing a role in the detoxification and excretion of drugs and xenobiotics. The fundamental physiologic molecule for the maintenance of the structural and functional activities of the liver. Glutathione is one of the primary factors determining cellular aging and life expectancy. more

Gnosis S.p.A. offers the product as bulk and finished formulation.

THQueenTM Glutathione chewing gums is the chewable form of glutathione that resists being broken down in the body before it reaches the bloodstream. Chewing gums enable rapid release of glutathione and easy absorption through the mouth, providing superior organoleptic properties and convenient way to get a daily dose of glutathione. more

SAGACETM (S-Acetyl Glutathione) is an alternative form of the reduced GSH. Several studies have shown that this precursor of GSH is well-absorbed and more stable throughout the digestive tract than the L-glutathione reduced and has a positive effect on many oxidative stress biomarkers.more


BiooptimaTM (Saccharomyces Boulardii)Go to Top

Saccharomyces boulardii is a non-pathogenic, non-colonizing yeast with probiotic properties used in many countries as both a preventive and therapeutic agent for diarrhoea and other gastrointestinal disorders

It has been extensively examined with more than several hundred studies for anti-diarrhoeal, intestinal anti-inflammatory and anti-infective agent.

It is a unique probiotic that is known to survive gastric acidity and resistant to proteolysis. Gnosis S.p.A. has US DMF for its product and it has been registered with the DCGI and offered as a pharmaceutical product in India. more


Biokyn® (Nattokinase) Go to Top

Biokyn® exclusive property of Gnosis, is natural Nattokinase fully obtained by fermentation process of Bacillus subtilis.

Nattokinase supports the fibrinolytic clearing system in the body which is responsible for healthy circulation, by helping to break down fibrin protein deposits in the bloodstream to promote and enhance healthy blood flow.

Nattokinase enhances the body’s natural ability to fight blood clots, and has an advantage over blood thinners because it has a prolonged effect without side effects. more


FDP (d-fructose-1,6-diphosphate)Go to Top

FDP is an important naturally occurring intracellular metabolite that concurs to increase ATP that plays a fundamental role in the creation of energy. It is obtained by fermentation process.

Exogenous FDP has been demonstrated to accelerate ATP production, to prevent glycogen breakdown, to stimulate glycogen synthesis, and to synthesize free fatty acids in animals and humans.

FDP by Gnosis S.p.A. is available as Dicalcium, and Magnesium salt for maintaining the metabolic and energetic requirement of athletes. more


D-MannoseGo to Top

D-Mannose is a naturally occurring rare sugar manufactured from wood-based or other biomass hydrolysates using an aqueous chromatographic separation process.

D-Mannose has been well studied for its efficacy in flushing out E.coli effectively and preventing re-occurrence of urinary tract infections.

DuPont™ Danisco® is the only manufacturer of Natural D-Mannose in the world. Since the product is completely natural, there are no side effects and it is safe even for Children and pregnant women. Danisco offers several grades of D-Mannose of which CM-20 grade is best suited for tablet formulations more


CranCan NC (Cranberry Extract)Go to Top

Cranberries are the native fruit of North America and are the most promising non-pharmacological way of preventing Urinary Tract Infection. They are known for high concentrations of anthocyanins and proanthocyanidins (PAC). Cranberry extracts are even safe for use in children and pregnant women.

Cranberry contains the highest amount of A-type PAC’s only type responsible in anti-adhesion effect against uropathogenic E.coli bacteria in UTI; whereas other fruits contain B-type PAC’s.

Nutra Canada offers highly purified cranberry extract – CranCan NC with A-type PAC’s responsible for anti-adhesion effect in UTI. They offer wide range of generic and branded cranberry extracts ranging from 1% to 80% PAC Type-A. more

UROPhenol™ is their branded range of cranberry extract with PAC content determined using the latest BL-DMAC method and guaranteed bioactivity. more


Tocomin SupraBio® (Tocotrienol – Vitamin E)Go to Top

Tocotrienol is known as ‘Super Vitamin E’ – 40-60 times greater antioxidant properties and higher efficacy as compared to α-tocopherol.

Carotech Bhd is the first and largest producer to commercially extract natural full spectrum palm tocotrienol complex.

Tocomin SupraBio® is patented and Bio-Enhanced to have an increase in absorption by an average of 250% of each individual Tocotrienols. It is the only tocotrienol source with actual published human tissue distribution clinical trial and absorption study , thus proving superior bioavailability and bio-efficiency.

The product has been clinically proven to have several benefits including Neuro-protection, Cardio protection, heart health, Liver health, Skin health, Hair health, etc. Carotech Bhd have several clinical studies on their product.

The product can be incorporated into Dietary Supplements, Food & Beverages, Cosmetics & Personal Care Products. more


Omega-3 fish oilGo to Top

Omega- 3s are essential fatty acids with several health benefits including brain, heart, eye, joints, etc.

AlaskOmega® – Organic Technologies offer a wide range of EE and rTG forms Omega-3 (up to 80% EPA and DHA) concentrates refined from wild Alaskan fish oils. They also offer Omega-3 concentrates customised to your need.

Caught in Alaska, Refined in Ohio. AlaskOmega® is MSC certified sustainable, 100% USA raw material source. The unique process results in extremely low fishy taste and slight or no reflux. The product is steam deodorized – Extremely low odour / odourless. more

kd-pür® – KD Pharma’s kd-pür® oil is produced using its patented technology based on Super Critical Fluid Chromatography (SFC) and Super Critical Fluid Extraction (SFE), without the use of excessive heat, chemical solvents or oxygen.

kd-pür® is available in different grades of highly pure and concentrated range of EPA and DHA (up to 99% pure). KD Pharma also offers generic grades of Pharmaceutical products Lovaza (in Nutra and Pharma grade) and AMR 101 (pharma grade) with DMF support. more


NKO® (Omega-3 Krill Oil)Go to Top

Krill oil is an extract prepared from a species of Antarctic krill, Euphausia superba.

The Omega-3 fatty acids in Krill oil are bound mostly to phosphatidylcholine. Krill oil is principally indicated for cardiac health. It also contains Astaxanthin, one of the most potent anti-oxidants and choline, good for cardiac and cognitive health. The krill Oil Omega-3 phospholipids have many fold higher efficacy for lowering LDL and Triglycerides, and raising HDL as compared to Fish oil at one-third the dose.

Other indications include inflammation, osteoarthritis, cognitive health (ADHD) and women’s health (PMS).

Neptune Technologies is the World leader in krill oil with the first commercially available product as Neptune Krill Oil (NKO®). NKO® with 100% purity represents the only clinically proven and scientifically acknowledged marine omega-3 phospholipids with cardiovascular, cognitive and anti-inflammatory benefits for human applications.

Neptune’s subsidiary firm Acasti Pharma also offers pharmaceutical grade krill oil capsules under the brand name CaPre® & medical food Onemia® for cardiovascular health.

Neptune offers combination products apart from its premium krill oil blend (NKO®). NKO® beat is NKO® fortified with CoQ10 for heart health, NKO® flex is NKO® fortified with Vitamin D for bone and joint health while NKO® focus is fortified with lutein for brain and eye health. more


Cynatine® HNS (Solubilized Ingestible Keratin) Go to Top

Cynatine® from Roxlor is a revolutionary cosmeceutical ingredient comprising of Solubilized Keratin, a protein found naturally in the body. Cynatine HNS supplements the body with bioavailable keratin which enhances health, protects and repairs damaged Hair, Nails and Skin.

The company is well known for its technological advancements and extraction process with which it is able to extract and the most bioavailable form of Keratin.

Hair Care: Cynatine HNS has been shown to reduce hair loss from washing, improve hair strength and improve the brightness and lustre of hair.

Nail Care: Cynatine has been shown to provide improved strength, elasticity and moisture retention to nails.

Skin Care: Cynatine reduces fine lines and wrinkles, promotes firmness and elasticity in skin, reduces redness from inflammation or sensitive skin, improves the brightness and radiance of skin.

Cynatine is highly soluble and absorbed by human body and is well supported with human studies conducted by Roxlor. It is produced via a patented process without using harsh chemicals. more


Replicine™ Functional Keratin® (External Keratin)Go to Top

Keraplast Technologies is the world’s leading innovator of Keratin Protein technology for external keratin for hair. Keraplast’s unique patented technology is able to produce keratin which has 91% homology to hair structure.

Replicine™ Functional Keratin® presents the hair with the exact building blocks needed for repair, rescue, renewal and protection in a form suitable to be delivered through a wide range of familiar hair care formulations.

Keraplast offers finished products in the form of repairing shampoo and conditioner, professional hair rescue treatment, smoothing system and Two Pot Hair Straightening System.

Keraplast also offers the Replicine™ Functional keratin® Ingredient Renew 2 along with a formulation guide to incorporate their ingredient into the formulation of choice. more


Yestimun® (Yeast Beta-Glucan)Go to Top

Yestimun® is the only yeast glucan worldwide that is extracted exclusively from raw materials conforming to the German purity law.

Yeast Beta-Glucan is well documented for its ability to boost immune system. It supports natural defences –builds immunity, reduces the risk of catching a cold during winter and improves anti-inflammatory cytokine.

Leiber is a European leader in manufacturing of high purity (>85%) natural Beta-Glucan produced by brewer’s yeast fermentation. The company has developed special patented drying processes for the products.

The product is GMO free, FDA GRAS, and Kosher certified. Leiber has significant clinical support to prove the efficacy of the product. more


Suntheanine® (L-Theanine)Go to Top

Suntheanine® is pure and natural L-theanine (found naturally in green tea).

Taiyo Kagaku is the leading producer Suntheanine® (> 99% L-Theanine). It is a patented dietary ingredient protected by several US and international patents.

Suntheanine is produced via a patented enzymatic process that mimics the natural process in green tea leaves resulting in > 99% pure L-isomer-theanine.

It has been extensively studied and targeted toward relaxation and mental focus. It naturally stimulates activity in the brain known as alpha waves, which are associated with a relaxed but alert mental state.

Additional proven health benefits are improving the quality of sleep, diminishing normal symptoms of premenstrual syndrome (PMS), improving learning performance, heightening mental acuity and supporting the immune system.

Suntheanine® was awarded the “Food Ingredient Research Award” at the 1998 Food Ingredients Europe and “Best New Product of 2000″ at Nutracon. It is Food Grade, non-GMO, GRAS and certified Kosher. more


Sunphenon® (Green tea extract)Go to Top

Sunphenon® offered by Taiyo Kagaku is a series of highly purified polyphenols rich in natural green tea catechins. It is obtained from the leaf of traceable green tea (Camellia sinensis).

These polyphenols have been shown to have numerous biochemical and physiological benefits, including antioxidant, anti-microbial, deodorant and thermogenic (fat burning) activities – by influencing metabolic activity of the body.

Sunphenon® has been approved by the Japanese Foundation for Health and Nutrition as a Food for Specified Health Use (FOSHU). Sunphenon® was further honoured with the Industrial Achievement Award by the U.S. Institute of Food Technologists (IFT).

Sunphenon® extracts are Food Grade, non-GMO and certified Kosher. more


PEAK ATP® (Oral ATP) Go to Top

PEAK ATP® is a clinically validated and patented form of Adenosine 5’-Triphosphate (ATP) Disodium for Sports Nutrition. ATP is called the “molecular unit of currency” of intracellular energy transfer.

PEAK ATP® is a branded, patented, and clinically researched nutraceutical ingredient from TSI Inc. identical in structure to actual human ATP.

It is the only form of oral ATP delivery shown to enhance athletic performance and recovery, improve well-being, and support healthy aging, through two proposed mechanisms of action: increasing muscle excitability and blood flow.

Studies have also shown that PEAK ATP® increases muscle strength and training volume during repeated high-intensity exercise, while reducing muscle fatigue.

Efficacy of this product is supported by various animal and human clinical studies. more


NovaSoy® (Soy Isoflavones)Go to Top

Isoflavones are natural plant nutrients that exhibit agonist and antagonist estrogenic mechanisms. Genistein and daidzein are two isoflavones found in the highest amount in Soybeans.

NovaSoy® is a brand of soy isoflavone from ADM from whole soybean that has been scientifically proven to reduce the frequency and severity of hot flashes. Only soy isoflavones derived from the whole soybean (not just the soy germ) have an effective amount of genistein in them.

Clinical studies show that Isoflavones have some of the same characteristics as human hormones. They often interact with estrogen receptors to produce similar effects in the body.

Soy isoflavones may also affect arterial health, contributing to a healthy cardiovascular system.more


CardioAid™ (Plant Sterols)Go to Top

Plant sterols are steroid compounds similar to cholesterol which occur in plants and when consumed, get in the way of dietary cholesterol being absorbed into the bloodstream.

ADM produces the CardioAid™ brand of plant sterols, a class of plant-derived compounds that have proven effective in blocking the absorption of cholesterol.

Studied for more than 50 years, plant sterols are proven to significantly lower cholesterol levels. Plant sterols are chemically similar to dietary cholesterol found in animal products and so when consumed they get in the way of dietary cholesterol being absorbed into the bloodstream.

CardioAid™ plant sterols can be added to a variety of formulations, dietary supplement, food & beverages, as a result of being GRAS.

FDA Health Claim – Daily consumption of a total of at least .8 grams of plant sterols in two meals may reduce the risk of heart disease when part of a diet low in fat and cholesterol. more

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